منابع مشابه
Glycosphingolipids of Human Gliomas1
Histologically characterized human gliomas of various grades of ma lignancy obtained during surgery were extracted, and their glycolipids were isolated and partially identified. Among the gliomas analyzed, three types of glycolipid component distribution could be identified. The glycosphingolipid (CSL) type I pattern correlated closely with that of the most malignant gliomas (Grade IV). Its neu...
متن کاملGlycosphingolipids: structure and function
Glycosphingolipids occur in most hi her organisms as 200 compounds in this class have been isolated and chemically characterized. In this aper, we compare the structures of several complex glycosphingoEpids and discuss the utilit of fast atom bombardment mass spectrometry in the MSldS mode with collision-assisted dissociation of the ceramide ion to study details of the ceramide structure. The f...
متن کاملGlycosphingolipids from cultured astroblasts.
The glycolipids of two clonal lines astroblasts, NN clone and C6 clone, were studied. Glucosylceramide and lactosylceramide were present at very low levels in both clones, but the most common myelin glycolipids galactosylceramide and sulfatide, were not detected. The ganglioside pattern of these cells was rather simple, with GM3 as main compoenent, accompained in one clone by GD3. These results...
متن کاملLipidomics of Glycosphingolipids
Glycosphingolipids (GSLs) contain one or more sugars that are attached to a sphingolipid moiety, usually to a ceramide, but in rare cases also to a sphingoid base. A large structural heterogeneity results from differences in number, identity, linkage, and anomeric configuration of the carbohydrate residues, and also from structural differences within the hydrophobic part. GSLs form complex cell...
متن کاملGlycosphingolipids as toxin receptors.
A number of proteins produced by certain bacteria and plants are potently toxic to mammalian cells. This toxicity results from their ability to catalytically modify macromolecules that are required for essential cellular functions such as vesicular trafficking, cytoskeletal assembly, signalling or protein synthesis. To reach their targets, these proteins bind specific surface receptors before e...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1991
ISSN: 1884-2003
DOI: 10.5650/jos1956.40.361